Sequence and antigenic variability of the Helicobacter mustelae surface ring protein Hsr.
نویسندگان
چکیده
We have identified an array of more than 500 repetitive sequences flanking the hsr gene, which encodes the major surface protein of the ferret pathogen Helicobacter mustelae. The repeats show identity exclusively to the amino-terminal half of Hsr. Analysis of Hsr from three strains indicated variability of exposed epitopes. Characterization of an hsr mutant showed that Hsr is not an adhesin.
منابع مشابه
Failure of surface ring mutant strains of Helicobacter mustelae to persistently infect the ferret stomach.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 69 5 شماره
صفحات -
تاریخ انتشار 2001